It is well known that music influences a person's mood, thoughts, feelings, and emotions. Depression is a mental disorder classified as a mood disorder, characterized by a range of cognitive, behavioral, affective, and psychosomatic symptoms. It is one of the most common mental disorders today, increasingly affecting children and young people. The impact of music on mood during this age can be very strong; therefore, targeted, appropriate, and directed use of music can significantly improve emotional and psychophysical states, as well as the overall quality of life in young people. Music therapy is a scientifically grounded discipline that uses music and musical elements for therapeutic purposes and has proven to be an effective therapeutic tool for adolescents with depressive disorders, a population particularly sensitive to emotional and psychological challenges. By employing various methods such as active listening, composition, and improvisation, music therapy provides adolescents with the opportunity to express emotions that are often difficult to verbalize. Through the analysis of relevant research and case studies, the benefits of music therapy are demonstrated, such as the reduction of depressive symptoms, improvement in emotional expressiveness, and enhancement of overall well-being in adolescents with depressive disorders. Through the presentation of research results, this paper confirms that music therapy can significantly contribute to improving the mental health of adolescents with depressive disorders, thereby opening up possibilities for its wider application in clinical practice.